LEP and metabolic syndrome: In addition, antipsychotic-induced extrapyramidal symptoms (DRD2, HTR2A, GRIK3, SLC6A4 VNTR, COMT Val158Met, ADORA1, ADORA3, ADORA2A), tardive dyskinesia (HTR2A, HTR2C, DRD2, DRD3, DPP6, SOD2, CYP2D6, CNR1, HSPG2), metabolic syndrome (HTR2C, LEP, LEPR), and other antipsychotic-induced symptoms have been associated with polymorphisms in several genes (DRD2, LEP, BDNF, LPL, TPH, etc.)[266].