IMMP2L and erectile dysfunction: In Holstein cattle on chromosome 4, the Inner Mitochondrial Membrane Peptidase 2-Like Gene (IMMP2L) had a negative effect on the cow conception rate [40]; in mouse, homozygous IMMP2L females were infertile due to defects in folliculogenesis and ovulation, whereas mutant males were severely subfertile due to erectile dysfunction [41].