Expression of one of the serine/arginine (SR) proteins—serine/arginine-rich splicing factor 1 (SRSF1)—is upregulated in several cancers and is positively correlated with tumour growth and lymph node metastasis; additionally, it is negatively correlated with the sensitivity of cancer cells to anti-tumour therapy. The gene discussed is RNPS1; the disease is neoplasm.