While the level of sIL-6R level was comparable in patients with MPA and GPA to controls, patients with active MPA and GPA exhibited a significantly higher median serum sIL-6R level than those with inactive disease (38.1 ng/mL vs. 34.7 ng/mL; p = 0.029) (Figure 5). The gene discussed is IL6R; the disease is granulomatosis with polyangiitis.