PRKN and Parkinson disease: The genes most often associated with PD are those for α-synuclein (SNCA) and leucine-rich repeat kinase 2 (LRRK2), with less prevalent mutations in Parkin (PRKN), PTEN induced kinase 1 (PINK1), Parkinson disease gene 7 (DJ-1), ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1), and ATPase cation transporting 13A2 gene (ATP13A2) [7,8].