We found that SDMA also associates with soluble TNF receptor (superfamily) concentrations, i.e., sTNF-R1, sTNF-R2, and sCD30/TNFRSF8 in a subsample of the population-based SHIP-TREND study, indicating that this interaction is not only evident at higher SDMA concentrations seen in patients with chronic kidney disease but also could be relevant within the normal range of SDMA concentrations, i.e., 0.27 and 0.63 μmol/L, 2.5th and 97.5th percentile, respectively, in women and 0.30 and 0.67 μmol/L, 2.5th and 97.5th percentile, respectively, in men [11]. Here, TNFRSF8 is linked to chronic kidney disease.