TNF and neoplasm: Compared with normal tissues, PDCD1, CD247, CXCL2, CXCL3, CXCL16, CXCL17, CCL20, and TGFB1 were highly expressed in tumor epithelial cells (Supplementary Figure S5); PDCD1, CD247, CCL4, CCL5, GZMB, GZMA, IFNG, NKG7, XCL1, and XCL2 were highly expressed in tumor T lymphocytes and natural killer cells (Supplementary Figure S6); PDCD1, CD247, CCL18, TNF, CSF1, IL10, and IL1A were highly expressed with tumor myeloid cells (Supplementary Figure S7); TGFB1 was highly in tumor fibroblasts (Supplementary Figure S8); and CSF3 was highly expressed in endothelial cells (Supplementary Figure S9).