For example, gene expression levels of COL1A1, COL6A3, and FN1 in CAFs as well as COL4A1 and COL4A2 in Angiogenic_EC were correlated with the proportion of the Cancer_Malig subtype in BC and CRC, indicating these pEMT tumor cells might be regulated by COL1A1 in CAFs and COL4A1 in Angiogenic_EC (Figure 5b,c, Supplementary Figure S14a, Supplementary Table S7). This evidence concerns the gene FN1 and colorectal carcinoma.