CCL2 and metabolic dysfunction-associated steatohepatitis: In mouse models of NASH induced by supplying various diets, including an atherogenic diet, methionine- and choline-deficient diet (MCD), high fat diet (HFD), and Western diet, activation of NLRP3 inflammosomes and subsequent production of IL-1β exacerbates inflammatory responses while increasing the IL-6 and CCL2 levels and the numbers of infiltrating MoMφ and neutrophils [132].