ANPEP and age-related macular degeneration: Recent investigations have explored the existence of APN/AdipoRs in ocular tissues [46,63], with a particular focus on its role in conditions such as DR, retinopathy of prematurity, the preservation of hypoxia-induced retinal neovascularization, photoreceptor integrity, retinitis pigmentosa, and AMD within the context of ocular pathophysiology.