MUC16 and Ovarian cyst: Again, both TPA and CA-125 were able to distinguish malignant cases from healthy controls, ovarian cysts, all benign or all non-malignant cases (all p < 0.001), resulting in AUCs of 0.879–0.954, as well as Sens90 of 65.7–88.6% and Sens95 of 48.6–88.6%.