Moreover, aMMP-8 can be analyzed in peri-implantitis diagnostics by traditional laboratory method immunofluorometric assay (IFMA) and modern rapid point-of-care/chairside diagnostics (aMMP-8 POCT), and both methods have shown aMMP-8 to be more precise (in terms of the area under the receiver operating curve (ROC)) than the other tested biomarkers (total MMP-8, polymorphonuclear (PMN) elastase, myeloperoxidase (MPO), tissue inhibitor of MMP (TIMP)-1, proMMP-9, aMMP-9) and bleeding on probing (BOP) (Figure 3, Table 1). Here, MPO is linked to Peri-Implantitis.