SLC2A1 and breast carcinoma: In breast cancer cells, it induced autophagy and apoptosis, decreased lactate and ATP levels, suppressed mRNA level and activity of hexokinase (HK), phosphofructokinase (PFK), and lactic dehydrogenase (LDH); decreased glucose consumption, GLUT1, and HIF1α; inhibited proliferation and xenograft growth [211].