PCBP2 and cancer: The fact that PCBP2 knockdown significantly increases the sensitivity to erastin-induced ferroptosis in cancer cells, whereas it reduces glutamate-induced apoptosis in neurons [38,50], points to a prominent dual antiferroptotic and proapoptotic role of PCBP2; the balance between the two processes probably depends on the cell type and its physiological status, with all of these together finally determining the cell fate.