Though the bad-CNA profile had equally poor prognosis both in the NEG and BCR::ABL1pos subgroup, the good-CNA profile was associated with much better survival in the BCR::ABL1pos patients (OS 89 ± 10%; RFS 89 ± 10%) when compared to the NEG ALL (n = 14, OS 28 ± 13%; RFS 31 ± 17%). This evidence concerns the gene BCR and acute lymphoblastic leukemia.