All of the BCR::ABL1-like ALL represented JAK::STAT2–class aberrations: 8 patients with overexpression of CRLF2 gene, 7 with P2RY8::CRLF2 rearrangement, 1 with CRLF2 gene point mutation, 6 with JAK2 (see details in Table S1). Here, CRLF2 is linked to acute lymphoblastic leukemia.