The distribution and frequencies of CNAs were generally consistent with those from other study cohorts in the whole series, as well as across genetic subgroups, with the highest CNA frequency in BCR::ABL1pos (80% CNA) and BCR::ABL1-like subgroups (83% CNA), intermediate in NEG B-ALL (69% CNA), while the lowest in patients with MLL rearrangements [2,33]. This evidence concerns the gene BCR and acute lymphoblastic leukemia.