IL6 and non-small cell lung carcinoma: The CRP turnover model predicted both the average and individual CRP concentrations under the steady-state assumption: only baseline IL-6, baseline TS, disease stage, and smoking status affected CRP production, i.e., for a non-smoker with stage IV NSCLC, baseline IL-6 of 2.57 pg/mL and TS of 8.25 cm (median values), Kin was estimated to be 0.297 (mg·L−1)·h−1, corresponding to a population steady-state baseline CRP concentration of 8.14 mg/L (Table 2) [41].