BRAF and neoplasm: Interestingly, the baseline characteristics that associate with a better tumor growth rate are LDH levels in blood prior to sampling, BRAF mutation status in the tumor, and the presence of lymphovascular and perineural invasion in the tumor, at least from a statistical significancy standpoint, suggesting that for these subsets, tumor growth rate plays a particularly important role in the final prediction of success, and that the threshold could be of more value.