Taking the hubs individually, the results showed that expression of two DEGs, upregulated small nuclear ribonucleoprotein Sm D1 (SNRPD1) and downregulated cofilin 2 (CFL2), was associated with pathological T stage (size of the tumor and any spread of cancer into nearby tissue) (Figure 8). The gene discussed is SNRPD1; the disease is neoplasm.