Using these molecular principles, Tsitsikov et al. compared transcriptional profiles of four of the most common benign types of meningiomas: (1) NF2 loss versus meningiomas with TRAF7 missense mutations, (2) NF2 tumors with or without additional loss of chr1p, and (3) TRAF7 meningiomas with additional missense mutations in AKT1 or KLF4. Here, AKT1 is linked to meningioma.