KLF4 and meningioma: Using these molecular principles, Tsitsikov et al. compared transcriptional profiles of four of the most common benign types of meningiomas: (1) NF2 loss versus meningiomas with TRAF7 missense mutations, (2) NF2 tumors with or without additional loss of chr1p, and (3) TRAF7 meningiomas with additional missense mutations in AKT1 or KLF4.