However, we found that 14-3-3 \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\upzeta /\updelta$$\end{document}ζ/δ was already upregulated in participants who only displayed amyloid-β accumulation in the CNS before tau aggregation or hippocampal atrophy appeared. This evidence concerns the gene MAPT and hippocampal atrophy.