Upon pooling overall survival data from the in-house HCC cohort and 14 other studies using a fixed-effects model, increased FOXM1 expression was confirmed as a risk factor for HCC patients, potentially affecting their prognosis (pooled HR value = 2.00, 95%CI 1.77–2.26, Supplemental Fig. 4A). The gene discussed is FOXM1; the disease is hepatocellular carcinoma.