In a publication examining the number of TP53 mutations in a population of NSCLC patients, there were a greater number of TP53 mutations in the DNA binding region of the p53 protein in codon 72 P/P homozygotes (65%), than heterozygotes, R/P (57%) and R/R homozygotes (40%), p = 0.01 [30]. This evidence concerns the gene TP53 and non-small cell lung carcinoma.