MYC and Miyoshi myopathy: Malignant MM also commonly contains somatic mutations in K- RAS, N-RAS, c-MYC and FAM46C (12.6% in AA and 8.3% in CA), BRAF-V600E (0.8% in AA and 4% in CA; of note, this may result in treatment decision differences) and deletions in chromosome 13q [10–12].