In five patients, fusion genes were identified, that have been described so far to occur sporadically (SPFQ::ZFP36L2 [18], XPO1::TNRC18 [19]) or not at all in AML (ETV6::CTNNB1, FUS::FEV, ZEB2::RUNX1). The gene discussed is RUNX1; the disease is acute myeloid leukemia.