A large proportion of AMLs (81%) were classified into common subtypes: AML with KMT2A-r, PML::RARA, RUNX1::RUNX1T1, CBFB::MYH11, mutations (m) of GATA1, CEBPA or NPM1, respectively. The gene discussed is KMT2A; the disease is acute myeloid leukemia.