Besides, the NPC2 expression was evaluated in normal cells including HaCaT and RGM-1 (Human gastric epithelial cell), and gastric cancer cells including MGC-803 (Human low differentiated gastric cancer), HGC-27 (Human undifferentiated gastric cancer), SGC-7901 (Human gastric cancer with lymph node metastasis), AGS (Untreated human gastric adenocarcinoma cells). This evidence concerns the gene NPC2 and metastatic malignant neoplasm in the lymph nodes.