However, VHL mutations have also been described in several other subtypes of renal cancer; for instance, tubulocystic RCC (TC-RCC) (17%) [13], papillary RCC (papRCC) (1.1%) [40], chrRCC (1.5%) [9], and FH-deficient RCC (1.8%) [41]. This evidence concerns the gene VHL and renal cell carcinoma.