Based on these results, fifteen key lnRNAs were screened for further validation in the TCGA STAD data, MC-40 and two GC cell lines (AGS, HGC-27), including lncRNAs (AXIN1, RELT, LPCAT1, MAMDC4, TNK2, NADSYN1, C12orf60, MC1R, THOP1, PNPLA6, MYH16, PLEKHM1P, SNHG7, RXRA, FGF22) (Table 2). This evidence concerns the gene FGF22 and gastric cancer.