FGF1 was reported to have antioxidative activities against diabetes associated NAFLD [21] and DOX-induced hepatoxicity [27], and hepatic oxidative stress was thought to paly causal roles in the development of DOX-induced hepatoxicity, since supplement of an antioxidant compound N-acetyl cysteine significantly attenuated DOX-induced liver damage [29,30,31]. The gene discussed is FGF1; the disease is diabetes mellitus.