FGF1 and metabolic dysfunction-associated steatotic liver disease: FGF1 was reported to have antioxidative activities against diabetes associated NAFLD [21] and DOX-induced hepatoxicity [27], and hepatic oxidative stress was thought to paly causal roles in the development of DOX-induced hepatoxicity, since supplement of an antioxidant compound N-acetyl cysteine significantly attenuated DOX-induced liver damage [29,30,31].