TNF and neoplasm: In Table 1 and Figure 3, AFB1 mainly activate apoptosis, by inducing several pathways: (1) oxidative stress, (2) mitochondrial pathway, (3) endoplasmic reticulum (ER) stress response, (4) Fas/FasL (Fas ligand) signaling pathway, (5) tumor necrosis factor-alpha (TNF-α) signal pathway (a key cytokine involved in inflammation, immunity, cellular homeostasis, and tumor progression) [31,32,33,34].