The KEGG enrichment analysis showed that the main signaling pathways involved in the common targets of MFEC and immunosuppression included the pathway in cancer, advanced glycation end products and their receptors (AGEs-RAGE) signaling pathway in diabetic complications, PI3K-Akt signaling pathway, tumor necrosis factor (TNF) signaling pathway, fluid shear stress and atherosclerosis, kapos sarcoma-associated herpes virus infection, hepatitis B and C, and prostate and pancreatic cancer. Here, TNF is linked to atherosclerosis.