TIMP1 and Hepatic fibrosis: The Enhanced Liver Fibrosis Panel (ELF) is a blood test consisting of three markers of matrix turnover: hyaluronic acid, tissue inhibitors of metalloproteinase 1 (TIMP-1), and aminoterminal peptide of pro-collagen 3 (PIIINP), and it performs well in detecting advanced fibrosis, with an AUROC of 0.90 [13].