The rs641738 C > T variant of the membrane-bound O-Acyltransferase domain containing 7 (MBOAT7), which is involved in phospholipid metabolism, is also associated with an increased risk of the entire spectrum of NAFLD [179,180], including higher chances of developing HCC in patients without advanced fibrosis [181]. This evidence concerns the gene MBOAT7 and metabolic dysfunction-associated steatotic liver disease.