There have been some promising results, revealing the discriminatory power of PTX3 in detecting stage 3–4 NAFLD, with AUROC values of 0.850 [74], and also its ability to evaluate the degree of liver fibrosis [75], with a further study showing the correlation between the values of PTX3 and NAFLD activity score and fibrosis stage [76]. This evidence concerns the gene PTX3 and fibrosis.