Cao et al. [2] showed that 10 long non-coding RNA (lncRNA)-transcription factor (TF) pairs including four glycolysis-related lncRNAs (FTX, long intergenic non-protein coding RNA 472, proteasome 20S subunit alpha 3 antisense RNA 1, and small nucleolar RNA host gene 14) and six TFs (forkhead box protein P1, SP1, MYC, FOX-M1, hypoxia-inducible factor 1 alpha [HIF1A], and FOS) are involved in the progression of human lung adenocarcinoma. Here, HIF1A is linked to lung adenocarcinoma.