Yaghoubi et al. found that 18F–FHBG can accumulate within glioma tumors [99], making transferred cells that express HSV1-tk detectable, and that it increased in sites of tumor recurrence, suggesting that CAR T cells migrated to the tumor sites, laying the foundation for further research into reporter gene imaging as a strategy to monitor the CAR T therapy of solid tumors, including NSCLC, in clinical practice. This evidence concerns the gene TKT and neoplasm.