WNK2 and colonic neoplasm: The anticancer effects of FBZ include the inhibition of p38-mitogen-activated protein kinase (MAPK) pathway activity and glucose metabolism in HeLa (cervical cancer) cells [11], ROS production in HL-60 (leukemia) cells [7,8], and G2/M phase arrest in 5-fluorouracil-resistant colon cancer cells SNU-C5 [10].