Throughout the study, trifuhalol A, isolated from AC, exhibited the significant effect of reducing the Th2-specific cytokine release from the lung and airways to reduce the formation of allergen-specific IgE, which are involved in the suppression of eosinophils and mast cells activation, leading to the protection of the respiratory system from the structural changes found in allergic asthma. The gene discussed is IGHE; the disease is allergic asthma.