MMP9 and atherosclerosis: It is speculated that the discovery of a substance that inhibits the activity of MMPs could bring vast benefits in the prevention and treatment of diseases that are dependent on these enzymes, and the aforementioned MMP-2 and MMP-9, along with other active products of adipose tissue such as tissue inhibitor of metalloproteinase (TIMPs-1), ox-IDL, high-sensitivity C-reactive protein (hsCRP), or isoprostane-8 and -15, could be considered as therapeutic targets with the potential to contribute to the regression of vascular disease and atherosclerosis at any stage of disease development [34,35].