Angiolin, under conditions of acute cerebral ischemia, exhibits pronounced endothelioprotective properties; it preserves the density of endotheliocytes, increases the concentration in the nuclei of RNA, increases the density of proliferating endotheliocytes (BrdU-test), increases the efficiency of utilization of endogenous L-arginine, and increases the expression of vascular endothelial factor (VEGF), as well as eNOS, and the presence of divalent sulfur in its structure determines the property of the NO scavenger [56]. The gene discussed is VEGFA; the disease is brain ischemia.