A proposed blood biological markers to be used in stroke (Table 2) diagnosis are CRP [107], matrix metalloproteinase 9 (MMP9) [103], cardiac troponin (cTnI), neuron-specific enolase (NSE) [108,109], brain natriuretic peptide (BNP) [109], glial fibrillary acidic protein (GFAP), S100 calcium-binding protein B (S100B) [110], lipoprotein-related phospholipase A 2 (Lp-PLA2) [13], nucleoside diphosphate kinase A (NDKA), PARK7 [111], aquaporin-4 (AQP4) [103], lactate dehydrogenase (LDH), and abnormal levels of hemoglobin (Hb), among other examples. The gene discussed is NPPB; the disease is Stroke.