In a study comparing liposarcoma and non-lipomatous sarcoma, PLIN2 was mostly positive in both groups, but PLIN1 was positive in more than two-thirds of liposarcomas but negative in non-lipomatous sarcomas, showing a statistically significant difference (p < 0.001), and its usefulness as a marker of adipocytic differentiation was reported by Westhoff et al. [15].These disease-specific features of PLIN1, as well as its well-understood mechanism of action, are the reasons that PLIN1 was chosen for the present study. Here, PLIN1 is linked to liposarcoma.