In their study on the presence of NF-H and soluble TNF receptor 1 that reflects the biological activity of TNF-α in subacute sclerosing panencephalitis, Matsushige et al. found a significant correlation between NF-H and sTNFR1 levels in the CSF of SSPE patients. The gene discussed is NEFH; the disease is subacute sclerosing panencephalitis.