MAPT and Alzheimer disease: Elsewhere, the anti-AD effects of Padina pavonica (P. pavonica), a brown seaweed, on mitochondrial function and protein aggregation have been investigated in an Aβ-induced SH-SY5Y cell model, with the results showing that pretreatment with the acetone extract of P. pavonica could protect mitochondrial membrane potential (ΔΨm), inhibit α-synuclein and tau protein aggregation, and ameliorate the aggregation of the Aβ peptide formation in Aβ-induced SH-SY5Y cells [95].