Moreover, in the latest genome-wide association study (GWAS) of MS, neutrophil cytosolic factor-4 (NCF-4) gene, encoding one of the subunits of the nicotinamide-adenine dinucleotide phosphate (NADP) complex in neutrophils, was discovered as a genetic factor susceptible to MS [95]. The gene discussed is NCF4; the disease is myeloid sarcoma.