A marked elevation in tau phosphorylation at multiple AD-like epitopes, such as pSer262, pSer214 and pSer356 and pSer199/202, has also been ascertained in COVID-19 brains in concomitance with the activation of several known tau-directed kinase, including the AMP-activated Protein Kinase (AMPK), Glycogen Synthase Kinase 3 beta (GSK3β), Protein Kinase A (PKA) and Calcium/Calmodulin-Dependent Protein Kinase II (CAMKII) [196]. This evidence concerns the gene GSK3B and Alzheimer disease.