In conclusion, we report several novel findings that were missed in the original articles: first, the immune signature of ICU and deceased patients is strikingly different than that of non-ICU patients, with notable absence of differences in many usual suspects such as IL-6, IFN-α2, CCL1, and CCL2 between non-ICU and ICU patients, whereas CCL5 exhibited sex differences in its expression levels in both HCW and COVID-19 patients. The gene discussed is IL6; the disease is COVID-19.