To further characterise whether the proinflammatory/pro‐tumour CD8+ T signature (Cd8a, Tnf, Ltb, Pdcd1, Il1b, Il6 and Cxcr6) existed in other mouse models of CLI, the Addmodule algorithm was also used to calculate the activity score of the proinflammatory/pro‐tumour CD8+ T signature in NASH mice using the online open‐access scRNA‐seq data (Figure S18A–C). The gene discussed is PDCD1; the disease is metabolic dysfunction-associated steatohepatitis.