Six studies (n = 481 participants) compared the level of serum AMH between girls with CPP and healthy controls (Fig. 2D), and there was low heterogeneity among the studies (I2 = 44%; P = 0.11).There was no significant association between CPP and the level of serum AMH (SMD: 0.07; 95% CI: -0.19 to 0.32; P = 0.61).Two studies (n = 108 participants) compared the level of serum AMH between girls with PT and healthy controls. This evidence concerns the gene AMH and central precocious puberty.