Further, this theory is in agreements with the work done by Krishna et al., [51] who in a retrospective cohort study analyzed NO2−/NO3− and H2O2 concentrations, transcript levels of endothelial NOS (eNOS)/iNOS, arginine modulators, and H2O2 regulators in PCOS women (N = 29) and non PCOS controls (N = 20). Here, NOS3 is linked to polycystic ovary syndrome.