To determine if the blockade of GCNT3 and, in turn, the expression and glycosylation of mucins can lead to increased susceptibility of tumor cells to immune system cellular components in terms of recognition and killing we established interaction platforms between KPC06 and 13KC mouse organoids and PBMCs isolated from syngeneic mice (Additional file 4: Figure S4). The gene discussed is GCNT3; the disease is neoplasm.