Objective: In the United States of America 1 in 10 people have been diagnosed with diabetes.1 Prolonged hypoglycemia can lead to severe complications including seizures, coma, and death.2 Antidiabetic agents like insulin,2 GLP-1 agonists,3 DPP-4 inhibitors,4 sulfonylureas4 and and SGLT-2 inhibitors5 have all been known to cause hypoglycemia, but no study has systematically compared hypoglycemia associations between different drug classes. The gene discussed is DPP4; the disease is Hypoglycemia.