GREM1 and cancer: The variant is in the vicinity of Gremlin1 gene (GREM1) and shown by QTLbase16 to be a blood expression QTL for Rho GTPase activating protein 11A (ARHGAP11A), a gene positioned near GREM1 and a methylation QTL for Eukaryotic Translation Initiation Factor 5A2 (EIF5A2), a gene whose overexpression correlates with multiple cancers including colorectal, gastric, and esophageal cancers.