Thus, a significant enrichment of GLI3 target genes within DEGs (~22.5%)17 and DEPs (~31.7%; Fisher’s Exact test p = 0.014) (Fig. 4e), as well as an enrichment of misexpressed IFT components also on protein level (Fig. 4d) further strengthens the relevance of altered PC function in sPD etiology. The gene discussed is GLI3; the disease is Platelet storage pool disease.