Our data show overexpression of CXCL10 in inflammatory regions compared to fibrotic regions in SSc-ILD lung tissues [Median (IQR): 4.7 (4.2–5.6) vs. 4.3 (3.6–4.7), P = 0.029] (Fig. 6). Here, CXCL10 is linked to interstitial lung disease.